特征
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优点
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转速可调5-80RPM,每次1RPM
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予以小鼠舒适的活动环境
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匀速,加速,多次加速模式(新)
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可用于研究运动学习机运动功能
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可使用USB闪存盘
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无需连接电脑即可储存数据
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新版软件
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新款触摸屏能够设置实验参数、管理实验数据。
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数据读取:
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液晶显示
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数据采集:
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52050-07 软件
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转棒开始:
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START (蓝色) 键
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电源:
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universal input 85-264 VAC, 50-60Hz, *大40 W
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转棒停止:
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RESET/STOP(红色) 键
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工作温度:
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10° - 40° C
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设置速度:
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功能键
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声级:
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< 60 dB
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速度重置:
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RESET/STOP (红色) 键
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打印:
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7145微型热敏打印机(需购置)
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转子:
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直径3cm转鼓
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|
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物理尺寸
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净重:
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11.0 Kg
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尺寸:
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46 (w) x 28 (d) x 33 (h) cm
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毛重:
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Kg 16.0 (approx.)
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包装尺寸:
转子
走道宽度
下落高度
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66 x 50 x 63 cm
直径3cm
5.7cm
16cm
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47650 小鼠转棒仪,包括:
47650 - 320 不锈钢感应槽
47650 - 302 说明书(在USB闪存盘内)
47650 - 010 专用软件包(在USB闪存盘内)
USB电源和电源线
可选:
如果您需要大、小鼠两种模型,您可以选择以下组合装:
47850组合装,包含一台小鼠转棒仪和一台大鼠转棒仪。
方法文献
§ N.W. Dunham & T.S. Miya: “A Note on a Sinple Apparatus for Detecting Neurological Deficit in Rats & Mice“ J. Am. Pharmaceut. Assoc., Scientific Edit., XLVI: No. 3, 1957
§ B.J. Jones & D.J. Roberts: “The Quantitative Measurement of Motor Inco-ordination in Naive Mice Using an Accelerating Rotarod“ J. Pharm. Pharmac.: 20: 302-304, 1968
使用转棒仪技术的相关文献:
§ B.J. Turner et alia: “Overexpression of Survival Motor Neuron Improves Neuromuscular Function and Motor Neuron Survival in Mutant SOD1 Mice” Neurobiol. Of Aging 35 (4): 906-915,2014
§ M. Milanese et alia: “Knocking Down Metabotropic Glutamate Receptor 1 Improves Survival And Disease Progression in the SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis” Neurobiology of Disease 64: 48-59, 2014
§ J.E. Lorenz: “Oxidant-Induced Activation of cGMP-Dependent Protein Kinase Iα Mediates Neuropathic Pain After Peripheral Nerve Injury” Antioxidants & Redox Signaling Jan. 2014
§ J.N. Justice et alia: “Battery of Behavioral Tests in Mice that Models Age-Associated Changes in Human Motor Function” Age Oct 2013
§ A.S. Hamlin et alia: “Lesions of the Basal Forebrain Cholinergic System in Mice Disrupt Idiothetic Navigation” PLoS ONE 8(1): e53472, 2013
§ T. Rantamäki et alia: “The Impact of Bdnf Gene Deficiency to the Memory Impairment and Brain Pathology of APPswe/PS1dE9 Mouse Model of Alzheimer’s Disease” PLoS ONE 8(7): e68722, 2013
§ T. Murakami et alia: “Vascular Endothelial Growth Factor Electro-Gene Therapy Improves Functional Outcome in a Mouse Model of ALS” Immunology, Endocrine & Metabolic Agents: 13 (2): 107-111, 2013
§ R. Günther et alia: “Clinical Testing and Spinal Cord Removal in a Mouse Model for Amyotrophic Lateral Sclerosis (ALS)” JoVE J. Vis. Exp. (61), e3936, doi:10.3791/3936, 2012//www.jove.com/video/3936/clinical-testing-spinal-cord-removal-mouse-model-for-amyotrophic
§ A.J. Grottick et alia: “Studies to investigate the role of 5-HT 2C Receptors on Cocaine- and Food-Maintained Behavior”: J. Pharmacol. Exper. Therap., 2000
§ L.T. Huang et alia: “Pentylenetetrazol-Induced Recurrent Seizures in Rat Pups: Time Course on Spatial Learning and Long…”: Epilepsia, 2002
§ E. Candelario-Jalil et alia: “Wide Therapeutic Time Window for Nimesulide Neuroprotection in a Model of Transient Focal Cerebral Ischemia in the Rat”: Brain Research: 177: 98-108, 2004
§ C.D. Heldermon et alia: “CliTherapeutic Efficacy of Bone Marrow Transplant, Intracranial AAV-mediated Gene Therapy, or Both in the Mouse Model of MPS IIIB” Molecular Therapy 15(5): 873-880, 2010 (rocking)
§ C.D. Heldermon et alia: “Development of Sensory, Motor and Behavioral Deficits in the Murine Model of Sanfilippo Syndrome Type B”: PLoS ONE: 8 (e772): 2007 (rocking)
动物行为分析软件:
VisuTrack软件
SuperMaze软件
FishTrack斑马鱼分析软件
动物行为仪器:
自身给药、条件恐惧、斯金纳、震惊反射(PPI)、跑步机、各类经典迷宫等
动物抓挠分析仪、动物震颤行为分析仪、动物捕食行为分析仪
动物主动步态分析、动物被动步态分析、动物自由步态分析(内测中)
睡眠剥夺仪、体温维持仪、智能热板仪、转棒疲劳仪、鼠尾光照测痛仪等
神经电生理:
光遗传、无线光遗传
光纤记录系统(单通道、多通道)
电生理信号采集系统(脑电、肌电等)
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